Saturday, October 28, 2017

The Sierra Club as a Religious Organization

Yes, and a good one, too.

The divides in the US have many dimensions, but a significant one is religious. Conservatives crow about their traditional religion- Christianity- and then, bizarrely, vote for Trump. What they really seem to be for is patriarchy and its traditional society-wide hierarchy (based on male-ness, but also on its accessory patriarchal religion and on race). Their model in the South shows that a bare-majority or even minority race can maintain power for decades in an ostensibly democratic society if enough levers of social, political, overt, violent, as well as covert power are used consistently. The movement against Confederate monuments is a watershed in consciousness of the thoroughgoing way the social gestalt of the South has been shaped by its treasonous and revanchist elite.

As far as rural and Southern America are concerned, the bicoastal elite live in another country entirely. In that country, we tend to think we have no narrative, no gestalt at all, but purely a functional this-is-the-way-it-is approach to reality and truth. A committment to reason, science, innovation, good public policy, social justice, etc. But of course, that can not be true. We have a narrative as well, and nothing illustrates it better than the Sierra Club.


This is the home of the shamans of environmentalism- the tree-huggers, whale watchers, and activists, inhabiting a completely different narrative from that of traditional Christianity and patriarchial conservatism. Its roots go deep into paganism and the natural reverence humans have for nature. It is a nature religion, but not animistic. There are no anthropomorphic deities or weird powers. We are the gods, but are fallen, now that we have inherited this awe-ful responsibility of taking care of a world that we have so hopelessly befouled. There is no bearded or other male figure behind the curtain. The Sierra Club conducts pilgrimiges, has its saints, sacred places and its version of the end-times, preaches to its believers, and expounds at every opportunity an ideology of love of and care for nature. It has its fetishes for untrammeled, unspoiled locations, its secret misanthropy, its revelations of human insignificance. And even jihad, if you count GreenPeace in the same sect.

A recent article by Gary Kamiya in the Sierra Club organ makes its religious nature particularly clear:
... Which takes us back to the wilderness within. No matter how refined we may think ourselves, at some level we are all still wild creatures, made up of the same materials as the mountains, the deserts, the oceans, the distant stars. "Wilderness" carries a connotation of chaos and anarchy, but that's misleading. Our inner wilderness is no more disorderly than the world itself is. A wild mind is a balanced mind. The wild world may be deeper and more heterogeneous than the city world, but the difference is only a matter of degree. The sense of wilderness is our birthright, and we can experience it anywhere. "The wilderness as a temple is only a beginning," Snyder writes. "One should not dwell in the specialness of the extraordinary experience . . . to enter a perpetual state of heightened insight." The real goal, he says, is to see all the land around us, whether in the country or in the city, as "part of the same territory—never totally ruined, never completely unnatural." 
Of course there is still absolutely nothing like a face-to-face encounter with deep wilderness. Once at Buck Lake, I was awakened by the screaming call of a pack of coyotes racing unseen through the 3 A.M. darkness, the shrill sound moving fast along the mighty granite ridge across from my campsite, then fading into the distance. That sound still rings in my memory, a quicksilver affirmation of the strangeness and holiness of the world.

The language and sentiments are clearly religious. But there is no theology, no theos at all. It suits the "spiritual-but-not-religious" mindset, whose sprituality is affective and natural, not burdened by over-thought (yet underbaked) theology and relic supernaturalism. Science isn't a problem here, but another way to appreciate the glory of what we love on so many levels- our world and biosphere.

Is all this good? People are naturally religious, creating and needing frames of meaning beyond mere subsistence and reproduction. The Republican Party and current administration shows what can happen when such a frame becomes completely moribund, paying lip service to Catholic and generally Christian dogmas while throwing any semblence of actual moral principle to the wind and practicing shameless greed. It is a revolting spectacle on every level. True religion fosters empathy and puts us in touch with our core values and commonality, not just among males, or with fellow countrymen, or even with humans, but with all beings.


  • Silent holocaust.
  • More lies.
  • Are human desires endless, and therefore work endless? Only if money is distributed equitably.
  • Does all our productivity get channelled to the top, or to those doing the work?
  • How to design drugs with knowledge and computers.

Saturday, October 21, 2017

Not the Last Dark Age- the One Before That

Review of 1177 B.C., by Eric Cline, about the decline and fall of the Bronze age around the Eastern Mediterranean

In this time of cultural and political decline, it is useful to contemplate previous cultural cataclysms. While "the Dark Ages" typically denotes the roughly five hundred year hiatus between the fall of Rome and the resurgence of wider cultural ties and development in Western Europe, that was hardly the only extended collapse of high level civilization. A previous Dark Age had followed the collapse of the Bronze Age circa 1200 BCE, leading to the several historically empty centuries before we hear about the classical Greek civilization rising from the ashes in the 700s BCE.

The Greeks cherished their dramatic sagas dating from that prior, heroic epoch, much as the English later looked backwards romantically via the Arthurian saga, going do far as to send Arthur to defeat the Romans in battle. But the battle of Troy was no fantasy- it really happened. The only question is whether it was part of the destruction of the Bronze age, or part of its normal, competitive, affairs.

In fact, it is astonishing what we do know about this age, given its distance from us and the ensuing civilizations. Eric Cline has assembled an excellent guide to this period, the late Bronze age, dredging up a great deal of scholarship old and new on the many civilizations clustered around the Eastern Mediterranean from Italy to Egypt. We owe particular debts to the writing developed earlier in this age, both the hieroglyphic style in Egypt, and the cuneiform style from Babylon, which was adopted by the Hittites and others. The clay tablets so amenable to preservation (especially after fires) have been a gold mine of knowledge about the affairs and attitudes of the time.

Hittite writing from about 3300 years ago, using cuneiform script.

We have correspondence between kings as well as more mundane accounts. We have in some cases both sides of a diplomatic exchange, even a momentous peace treaty between Egypt and the Hittite empire. It is quite amazing. These unearthed records paint a picture of extensive contacts and trade between the states of Cyprus (Minoans), the Mycenaeans of mainland Greece, the Hittites of Anatolia, the Assyrians, the Ugaritic state in what is now the northern Syrian coast, the Canaanites, and Egypt. It is easy to get carried away with globalization analogies and complexity theory. But unfortunately, we have very little to go on when it comes to what ended this period. The Egyptians record enormous battles with "the Sea Peoples", which seems to have been a coalition of several enemies. But they also say they won this war, and the pharoah, Ramses III, was laid to rest in high style, though murdered in an internecine plot. Cline goes through a large amount of archealogical evidence, which shows earthquakes, drought and climate change, internal revolt as well as external invasions during these times. It is, in sum, hard to finger any single cause for the eventual decline of all these cultures into several hundred years of relative silence and decreptitude, (not to mention tomb-robbing), though there may have been a combination.

It was once fashionable to cite the Sea People as the instigators, in an orgy of rapine and destruction, as is related in the Iliad, and the Egyptian annals. It is not clear who the Sea Peoples were, however. They may have been Myceneans, but evidently encompassed other groups as well, maybe even free-booting pirates. And the various destroyed cities of this age were not all invaded, let alone by these groups. The Hittites were sacked by other enemies.


Ramses III mortuary relief showing prisoners from battles with the "Sea Peoples". Note the diverse head-dresses.

Cline resorts to the decline of trade, and complexity theory in his speculations. But a problem is that, despite the excitement of finding trade relations between these states, and royal correspondence, it is highly unlikely that a state like Egypt was substantially dependent on outside trade or other assistance. Such relations were icing on the cake, but hardly fundamental to its perpetuation. The cause has to be found elsewhere, either in general theories of cultural sclerosis and decline, or perhaps in disease or technological innovation. Also, if invasions or revolts were at issue, why did some other state not take advantage of them? The preceding centuries had seen a constant tug-of war between Egypt and the Hittites for control up the Levant, indicating that, were one weakened, others would rush to take up the slack. Yet both went into decline, and the Hittites vanished completely. It may indeed just be a coincidence that many cultures had reached a high level simultaneously, and then at similar times were overcome by ruder powers less inclined to leave historical traces.

The stage of the Bronze age was originally set by the migration of Indoeuropean peoples into the Middle East, founding the Mycenean and Hittite cultures, among others. Their earlier spread was enabled by a suite of decisive technological innovations like horse riding, wheeled carts and chariots, mobile warfare, and herding, which enabled mobility and military success. By the late Bronze age, these were no longer novel and had diffused all over the region. But perhaps some other innovation, like improved and larger ships or nascent iron working, may have tipped a critical balance. Secondly, herding and livestock domestication generated a variety of new diseases, which eventually played such a large role in the destruction of the native peoples of the New World. Perhaps one of these diseases had yet to burn its way through the late Bronze age Mediterranean. It must be said, however, that such an event would probably show up in the Egyptian annals, and also that other cultures managed to recover within a generation or two from devastating plagues, such as the black plague.

Lastly, cultural decline might be inevitable after a long period of stability. Stability breeds complacency and a cultural dynamic where the powerful stay powerful, with ever less merit and justification as time goes on. Their corruption, combined with the resentment of the powerless, can lead morons into power, a bad sign in any age and a sure path to decline, for all their protestations of greatness.

Sunday, October 15, 2017

What Adulthood Looks Like in the Brain

A gene expression turning point in the mid-20's correlates with onset of schizophrenia, among other things.

Are brains magic? No. They may be magic-al in how they bring us the world in living color, but it is mechanism all the way down, as can be seen from the countless ailments that attack the brain and its functions, such as the dramatic degradation that happens in boxers and football players who have been through excessive trauma. All that amazing function relies on highly complex mechanisms, but we are only beginning to understand them.

One way to look at the brain is through its components, the proteins expressed from our genomes. Those proteins run everything, from the structural building program to the brain's metabolism and exquisitely tuned ion balances. Current technology in molecular biology allows researchers to tabulate the expression of all genes in any tissue, such as the brain or parts thereof. This is sort of like getting a quantitative parts list for all the vehicles active in one city at a particular time. It might tell you a little about the balance between mass transit and personal cars, and perhaps about brand preferences and wealth in the city, but it would be hard to conclude much about detailed activity patterns or traffic issues, much less the trajectories or motivations of the individual cars- why they are going where they are going.

So, while very high-tech and big-data, this kind of view is still crude. A recent paper deployed these methods to look at gene expression in the brain over time, in humans and mice, to find global patterns of change with age, and attempt to correlate them with diseases that are known to have striking age-related characteristics, like schizophrenia.

They duly found changes of gene expression over time, and tried to concentrate on genes that exhibit dramatic changes, reversing course over time, or plateauing at times that they call turning points. Below are a few genes that show a dramatic decline in mice, from youth to adolescence.

Expression of selected proteins in frontal cortex of mice, with age, showing turning points in early adulthood, which is about five months here in mice. These genes each have variants or other known associations with schizophrenia.

Perhaps the most interesting result was that, if they tabulate all the cases of turning points, most seem to occur at early adulthood. The graphs below show rates of genes with turning points at various age points. One can see that by about age 30 and certainly 40, (about age 7 months in mice), the brain is set in stone, gene-wise. There is little further change in gene expression.

Number of genes by age when their expression shifts direction, either up, down, or plateauing.

In contrast, age 15 to 30 is a very active time, with the most genes changing direction, and the largest changes of expression peaking about age 28. Given the many genes and complex patterns available, the authors reasoned that they could do some reverse engineering, predicting a sample's age from its expression pattern. And using only 100 genes, they show that they can reliably estimate the age of the source, within about 5 years. Secondly, they broke the gene sets down by the cell type where they are expressed, and found distinct patterns, like genes typical of endothelial cells attaining peaks of expression very early, before 10 years of age, as physical growth of the brain is maximal, while genes typical of pyramidal neurons, one of the most important and complex types of neurons, reach their inflection points much later, in the mid-twenties.

Types of genes and their rough times of expression shift, by age. Most key neuronal genes seem to settle into unchanging patterns in early adulthood. PSD is post-synaptic density, typical of synapses where learning takes place.

Particularly interesting to the authors are genes associated with post-synaptic density, part of the learning and plasticity system where connections between neurons are managed. These genes were especially enriched with turning points in early adulthood, and also feature a disproportionate number of genes implicated in schizophrenia, whose onset occurs around this time. The genes tended to be turned down at this time, in neurons. While these observations correlate with the age-specific nature of schizophrenia, they do not go much farther, unless it could be shown that the genetic variants that confer susceptibility are perhaps mal-regulated and more active than they are supposed to be, or some other mechanism that makes the connection between the defect (all of which so far which have very weak effects), and the outcome. For example, one such variation was found to increase expression of its gene, which is present and functional in the post-synaptic densities.

It is interesting to see the developmental program of our brains portrayed in this new way, but it is only a glimpse into issues that require far more detailed investigation.


Sunday, October 8, 2017

Vegas

A brief post.

Since no ideological, political, or religious motive has yet emerged for the massacre in Vegas, I would tend to interpret it as a terminal case of gun nuttery. We have long heard how violent video games and movies were supposed to be damaging our brains. Well, I think gun fetishization is an even stronger deranging influence. One can read it in the gun blogs, where a discourse of fear and power, of tactical preparedness and no retreat turn into a machismo echo chamber. And actually owning guns seems to have similar effects, turning owners minds to the power they wield, somehow generating the need for more and more, and more elaborate fantasies of what to do with them. Apparently 3% of gun owners own half the guns in the US. It is a disease, is culpable, and should be in the DSM.